Rift

It's a WoW clone. No twists, no gimmicks, just plain WoW - improve the graphics, change the classes a bit, set it somewhere else, you have Rift. Their tagline "We're not in Azeroth anymore" pretty much describes the biggest difference between the games. It looks polished and it's probably the best WoW clone to date, but it's not doing anything to change the face of the genre and I'm really skeptical about it. Most current MMOs don't follow a subscription model simply because people aren't likely to keep multiple subscriptions and they can't compete with WoW.