Ask a Magician Thread.

Big Bang alone should do more DPS than Paralyze alone; if you consider DoT, Paralyze's base DPS is still lower than Big Bang and since DoT from Paralyze can't stack with itself, you should use Paralyze to invoke the paralysis, and DoT, and follow up with Big Bangs for more DPS. I think Fire Demon -> Paralyze -> Big Bang would be most effective. Fire Demon has the longest timer, and thus if you use it after Paralyze, you waste some of the paralysis timer that should be spent charging Big Bang up. I honestly see no reason to use a Poison Staff unless it increases DoT, and even then, most monsters will die before the DoT is finished.

Um

Paralyze = 1292% dps + 160% @ 100% mastery poison, 350% range, 5 second stun, allows free tele casting, damage reduction on multiple mobs.
Big Bang = 1264% dps, 200% range on either side, no stun, requires charge up, cannot be freely telecasted.

Big Bang should be more useful at Lionheart Castle where mobs don't die in 2 hits, but Paralyze is definitely more useful on single targets and for other training areas. Fire Demon isn't all that useful anymore since Paralyze mobs, unless you need a fire weakness to 1hko with Big Bang.