ITT: Epic Vidya Gaem Boss Fights.

Speaking of Resident Evil...

Resident Evil 4 has some really fun bosses (insanely fun game, period). I think the most fun was fighting Krauser. He's so awesome. Nothing in that game is really that hard (even in Pro mode), but it surely does have some epic battles.

Part 1

Part 2

Awww, that guy is cheap using the Chicago Typewriter. It's a lot more fun using a pistol and trying to dodge all his attacks.