The Binding of Isaac: Rebirth

Started playing it, thought "huh this isn't so bad"
Wasn't until like floor 5 or 6 before I realized what was going on.

I'm now on floor 53. I have pretty much every item available to me at this point in the game.

I've made absolutely no progress whatsoever thanks to this seed, but it is a very, very good way of finding out what some of the new items do, and discovering item combinations.

Yep it's awesome. You know the item pool is empty when all you get is Breakfast. Apparently that's the "there's nothing left!" item.

Sounds like it would be a good seed to use if you were looking for those last few items to finish out the Platinum God achievement... not that anyone will be anywhere close to achieving it any time soon though, lol.

Can't get achievements during Challenges (except the clear achievement) nor Seed Set runs.

I thought runs using seeds didn't count for items?

And am I crazy, or is mom's heart much more like a bullet hell game? I seriously don't remember her firing so many shots on the flash game.

Mom's Heart used to be extremely pathetic. I can understand why it was buffed.

My first heart takedown was with the Guppy costume thingy, spewing flies like crazy and controlling a super powerful Ludovico tear. I was at a point where nothing even came close to touching me.

Guppy OP. You just need to get 3 Guppy items throughout the run. Use items count too, even if you don't hold on to them. I buy them even if I'm not going to use them in anticipation of getting 3, unless I seriously need hearts. If you get Guppy the run is pretty much won. Guppy gives Attack Flies on Hit, On Kill, and On Taking Damage, as well as Flying. It's OP as fu'ck.