Diablo III: Reaper of Souls

Is there an alternative to CoTA that makes you use single targer damage instead of AoE?

If you mean more single target than AoE then not that I know of. The other popular spots are also pretty AoE heavy (Cath, Audience, Core). Core might be slightly less AoE than the others.

EDIT:
Brb killing myself.
Still no pineappleing eye and I've even started soloing T4 solely for the increased drop rate.