South Park: The Stick of Truth

I definitely preferred Butters over the other 3 primary buddy choices (Jimmy felt really lacking in offensive ability, Stan couldn't hurt bosses for a while after I got him (he did become useful later when he could actually hurt enemies, but by then he was always outclassed by Kyle or Kenny for AOE)...Kenny was decent, but so many things were resistant to Gross that I stopped really using him for anything (especially considering how weak his bow attacks were). Kyle hit like a truck with his "elemental" attack and Rain of Arrows would almost always kill or cripple most normal enemies. I didn't ever really use Cartman, but he seemed like a liability with his extremely low health.

Something super funny and detailed about Cartman is that if you used a healing item on him, it had double effectiveness, because he's a fat bastard who eats 2 helpings rather than one. (though it only uses up one item). I only saw it happen with Cheesy Poofs, but I imagine it happened with the others too.